Which of the following cells is not an antigen-presenting cell (APC)?

• A. Dendritic cell
• B. Neutrophil
• C. B cell
• D. Macrophage

Answer: (B)

Verified step by step guidance

1. Step 1: Understand what an antigen-presenting cell (APC) is. APCs are immune cells that process and present antigens on their surface to T cells, initiating an adaptive immune response.
2. Step 2: Identify the common types of APCs. The primary APCs include dendritic cells, macrophages, and B cells, all of which can present antigens using MHC class II molecules.
3. Step 3: Review the role of neutrophils. Neutrophils are primarily involved in innate immunity and act as phagocytes to engulf pathogens, but they do not typically present antigens to T cells.
4. Step 4: Compare each cell type in the list to the definition of APCs. Dendritic cells, macrophages, and B cells all function as APCs, while neutrophils do not.
5. Step 5: Conclude that neutrophils are not antigen-presenting cells because they lack the necessary machinery and function to present antigens to T cells.