A drug that inhibits mitosis, such as griseofulvin, would be more effective against which of the following organisms?

• A. Bacteria
• B. Fungi
• C. Viruses
• D. Protozoa

Answer: (B)

Verified step by step guidance

1. Step 1: Understand the mechanism of the drug griseofulvin, which inhibits mitosis by interfering with microtubule function during cell division.
2. Step 2: Recall that mitosis is a process of eukaryotic cell division, involving the separation of chromosomes into two daughter cells.
3. Step 3: Identify which organisms undergo mitosis: fungi and protozoa are eukaryotes and perform mitosis, while bacteria (prokaryotes) divide by binary fission, and viruses do not undergo cell division as they replicate inside host cells.
4. Step 4: Recognize that griseofulvin targets fungal cells specifically by disrupting their mitotic spindle, making fungi more susceptible to this drug.
5. Step 5: Conclude that since fungi undergo mitosis and are affected by microtubule inhibitors, griseofulvin would be more effective against fungi compared to bacteria, viruses, or protozoa.