14. DNA Synthesis

Which of the following statements is/are correct with regard to individuals with the disorder xeroderma pigmentosum?

Which set of enzymes is involved in nucleotide excision repair?

The incorporation of an incorrect base into the DNA during replication __________.

As a result of proofreading by DNA polymerases, the overall error rate in the completed DNA molecule is approximately __________.

In a comparison between asexually reproducing bacteria and sexually reproducing multicellular eukaryotes, uncorrected errors in replication are more likely to be transmitted to subsequent generations in bacteria than in multicellular eukaryotes. Which of the following provides the best evidence-based explanation for this difference?

What aspect of DNA structure makes it possible for the proteins of nucleotide excision repair to recognize many different types of DNA damage? (d) the regularity of DNA's structure

What aspect of DNA structure makes it possible for the proteins of nucleotide excision repair to recognize many different types of DNA damage? (c) the energy differences between correct and incorrect base pairs

What aspect of DNA structure makes it possible for the proteins of nucleotide excision repair to recognize many different types of DNA damage? (b) the antiparallel orientation of strands in the double helix

What aspect of DNA structure makes it possible for the proteins of nucleotide excision repair to recognize many different types of DNA damage? (a) the polarity of each DNA strand

The spontaneous loss of amino groups from adenine in DNA results in hypoxanthine, an uncommon base, opposite thymine. What combination of proteins could repair such damage? a. nuclease, DNA polymerase, DNA ligase b. telomerase, primase, DNA polymerase c. telomerase, helicase, single-strand binding protein d. DNA ligase, replication fork proteins, adenylyl cyclase

The graph that follows shows the survival of four different E. coli strains after exposure to increasing doses of ultraviolet light. The wild-type strain is normal, but the other strains have a mutation in either a gene called uvrA, a gene called recA, or both. (b) What are the relative contributions of these genes to the repair of UV damage?

The graph that follows shows the survival of four different E. coli strains after exposure to increasing doses of ultraviolet light. The wild-type strain is normal, but the other strains have a mutation in either a gene called uvrA, a gene called recA, or both. (a) Which strains are most sensitive to UV light? Which strains are least sensitive?