Indicate whether each statement is true or false. If the statement is false, change the underlined word or phrase to make the statement true.


_____ Type III hypersensitivity reactions may lead to the development of glomerulonephritis.

Verified step by step guidance

1. Understand what Type III hypersensitivity reactions are: These are immune complex-mediated reactions where antigen-antibody complexes deposit in tissues, leading to inflammation and tissue damage.
2. Recognize that glomerulonephritis is an inflammation of the glomeruli in the kidneys, which can be caused by immune complex deposition.
3. Connect the dots: Since Type III hypersensitivity involves immune complex deposition, it can indeed lead to conditions like glomerulonephritis.
4. Evaluate the statement: Given the connection between Type III hypersensitivity and glomerulonephritis, the statement is true.
5. If the statement were false, identify the incorrect part and replace it with the correct term. In this case, no replacement is needed as the statement is true.

Key Concepts

Type III Hypersensitivity

Type III hypersensitivity, also known as immune complex-mediated hypersensitivity, occurs when antigen-antibody complexes accumulate in tissues, leading to inflammation and tissue damage. This type of reaction is typically associated with autoimmune diseases and can result in conditions such as glomerulonephritis, where the kidneys become inflamed due to these immune complexes.

Glomerulonephritis

Glomerulonephritis is an inflammation of the glomeruli, the tiny filtering units in the kidneys. It can be caused by various factors, including infections, autoimmune diseases, and hypersensitivity reactions. The condition can lead to symptoms such as hematuria, proteinuria, and impaired kidney function, making it a significant concern in the context of Type III hypersensitivity.

Immune Response

The immune response is the body's defense mechanism against pathogens and foreign substances. It involves various cells and proteins, including antibodies, that recognize and neutralize threats. Understanding the immune response is crucial for comprehending how hypersensitivity reactions occur and their potential consequences, such as tissue damage in conditions like glomerulonephritis.