A scientist is analyzing the cells from a granuloma tissue sample. Which type of immune cell is the scientist least likely to find in this sample?

• A. T cells.
• B. Macrophages.
• C. Neutrophils.
• D. Giant cells.

Answer: (C)

Verified step by step guidance

1. Understand the composition of a granuloma: Granulomas are organized structures formed during chronic inflammation, typically composed of macrophages, T cells, and sometimes giant cells.
2. Recognize the role of macrophages: Macrophages are a key component of granulomas, often transforming into epithelioid cells or fusing to form multinucleated giant cells.
3. Identify the involvement of T cells: T cells, particularly CD4+ T helper cells, are crucial in orchestrating the immune response within granulomas by releasing cytokines that activate macrophages.
4. Consider the presence of giant cells: Giant cells are formed by the fusion of macrophages and are commonly found in granulomas, contributing to the structure and function of the granuloma.
5. Evaluate the role of neutrophils: Neutrophils are typically involved in acute inflammation and are less likely to be present in granulomas, which are associated with chronic inflammation.