Indicate whether each statement is true or false. If the statement is false, change the underlined word or phrase to make the statement true.


________ Cyclosporine is released by degranulating mast cells.

Verified step by step guidance

1. Identify the role of mast cells in the immune system, particularly their function in releasing chemical mediators during allergic reactions.
2. Understand what degranulation means in the context of mast cells, which involves the release of substances stored in granules.
3. Research the substances typically released by mast cells during degranulation, such as histamine, cytokines, and other inflammatory mediators.
4. Examine the function and origin of cyclosporine, which is an immunosuppressant drug used to prevent organ transplant rejection.
5. Determine whether cyclosporine is a substance released by mast cells or if it is produced and used in a different context, and correct the statement if necessary.

Key Concepts

Mast Cells and Degranulation

Mast cells are a type of white blood cell that play a crucial role in the immune response, particularly in allergic reactions. Degranulation is the process by which mast cells release granules containing histamine and other mediators into the surrounding tissue, leading to inflammation and other immune responses. Understanding this process is essential for evaluating statements related to mast cell function.

Cyclosporine

Cyclosporine is an immunosuppressive medication primarily used to prevent organ transplant rejection and to treat autoimmune diseases. It works by inhibiting T-cell activation and proliferation, rather than being released by mast cells. Recognizing the role and mechanism of cyclosporine is vital for accurately assessing its association with mast cells.

True/False Statements in Biology

In biology, true/false statements often require a clear understanding of the relationships between different biological entities and processes. Evaluating such statements involves critical thinking and knowledge of specific facts, such as the functions of cells, the roles of various substances, and the mechanisms of action of drugs. This skill is essential for accurately determining the validity of scientific claims.