Indicate whether each statement is true or false. If the statement is false, change the underlined word or phrase to make the statement true.


_____ Candida albicans generally causes localized opportunistic infections but can become systemic, particularly in the immunocompetent.

Verified step by step guidance

1. Identify the key terms in the statement: 'Candida albicans', 'localized opportunistic infections', 'systemic infections', and 'immunocompetent'.
2. Recall that Candida albicans is a fungal pathogen known to cause opportunistic infections, which are infections that occur more frequently or are more severe in individuals with weakened immune systems.
3. Understand that 'localized opportunistic infections' means infections confined to a specific area, while 'systemic infections' involve the spread of the pathogen throughout the body.
4. Evaluate the phrase 'particularly in the immunocompetent'—immunocompetent individuals have a normal functioning immune system, so systemic infections by Candida albicans are less common in them.
5. To correct the statement if false, replace 'immunocompetent' with 'immunocompromised' to accurately reflect that systemic Candida infections are more likely in individuals with weakened immune defenses.

Key Concepts

Candida albicans and Opportunistic Infections

Candida albicans is a fungal organism commonly found as part of the normal human microbiota. It usually causes localized opportunistic infections, such as oral thrush or vaginal candidiasis, especially when the host's immune defenses are weakened.

Systemic Candidiasis and Immunocompromised Hosts

Systemic infections by Candida albicans occur when the fungus enters the bloodstream and spreads throughout the body. These severe infections primarily affect immunocompromised individuals, such as those with HIV/AIDS, cancer, or undergoing immunosuppressive therapy.

Immunocompetent vs. Immunocompromised Hosts

An immunocompetent host has a fully functioning immune system capable of fighting infections effectively. In contrast, immunocompromised hosts have weakened immune defenses, making them more susceptible to opportunistic pathogens like Candida albicans causing systemic disease.