Textbook Question
Label the following as granulocytes or agranulocytes and classify them as innate or adaptive cellular responders.
Basophil
Monocyte
Macrophage
Lymphocyte
Neutrophil
Eosinophil
Mast cell
NK cell
T cell
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19. Innate Immunity
Cells of the Immune System: Agranulocytes
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Which type of agranulocyte is primarily targeted and destroyed by HIV/AIDS?
A
B lymphocytes
B
Monocytes
C
Natural killer (NK) cells
D
CD4+ T lymphocytes (helper T cells)
Verified step by step guidance1
Understand the classification of white blood cells: Agranulocytes include lymphocytes and monocytes, which lack visible granules under a microscope.
Recall that lymphocytes are divided into B cells, T cells, and natural killer (NK) cells, each with distinct roles in the immune response.
Identify that HIV primarily targets cells expressing the CD4 receptor, which is a surface protein found on helper T cells (a subset of T lymphocytes).
Recognize that helper T cells (CD4+ T lymphocytes) are crucial for coordinating the immune response by activating other immune cells.
Conclude that the agranulocyte primarily targeted and destroyed by HIV/AIDS is the CD4+ T lymphocyte (helper T cell), not B lymphocytes, monocytes, or NK cells.
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