Indicate which statements are true. Correct all false statements by changing the underlined words.
__________ Rubor, calor, swelling, and dolor are associated with fever.

Verified step by step guidance

1. Step 1: Identify the terms given: rubor, calor, swelling, and dolor. These are classical signs of inflammation, not fever.
2. Step 2: Understand the definitions: 'Rubor' means redness, 'calor' means heat, 'swelling' is tumor, and 'dolor' means pain. These are the four cardinal signs of inflammation.
3. Step 3: Recognize that fever is a systemic response characterized by an increase in body temperature, not localized signs like rubor or swelling.
4. Step 4: Correct the statement by replacing the word 'fever' with 'inflammation' to accurately reflect the association of these signs.
5. Step 5: Summarize that rubor, calor, swelling, and dolor are associated with inflammation, not fever.

Key Concepts

Signs of Inflammation

Rubor (redness), calor (heat), swelling, and dolor (pain) are classic signs of inflammation, a localized tissue response to injury or infection. These signs result from increased blood flow, vascular permeability, and immune cell activity at the affected site.

Fever as a Systemic Response

Fever is a systemic increase in body temperature regulated by the hypothalamus, often triggered by pyrogens during infection. Unlike inflammation, fever affects the whole body and is not characterized by localized redness or swelling.

Difference Between Local and Systemic Immune Responses

Local immune responses, such as inflammation, occur at the site of injury or infection and involve visible signs like rubor and swelling. Systemic responses, like fever, involve the entire body and do not produce localized signs but help enhance immune function.