Indicate which statements are true. Correct all false statements by changing the underlined words.
__________ Opsonization occurs when a phagocyte’s pseudopods surround a microbe and fuse to form a sac.

Verified step by step guidance

1. Understand the definition of opsonization: it is the process by which pathogens are marked (tagged) for ingestion and destruction by phagocytes, typically through the binding of opsonins like antibodies or complement proteins to the microbe's surface.
2. Analyze the given statement: 'Opsonization occurs when a phagocyte’s pseudopods surround a microbe and fuse to form a sac.' This describes the physical engulfment process, which is actually called phagocytosis, not opsonization.
3. Identify the incorrect term: the underlined word 'Opsonization' should be replaced with 'Phagocytosis' because the statement describes the engulfment step, not the tagging step.
4. Rewrite the corrected statement: 'Phagocytosis occurs when a phagocyte’s pseudopods surround a microbe and fuse to form a sac.'
5. Summarize the distinction: opsonization enhances phagocytosis by marking microbes, while phagocytosis is the actual process of engulfing and internalizing the microbe.

Key Concepts

Opsonization

Opsonization is the process where pathogens are marked for phagocytosis by molecules called opsonins, such as antibodies or complement proteins. These opsonins bind to the microbe's surface, enhancing recognition and attachment by phagocytes, but opsonization itself does not involve pseudopods forming a sac.

Phagocytosis Mechanism

Phagocytosis is the cellular process where phagocytes engulf and digest microbes. It involves the extension of pseudopods around the microbe, which then fuse to form a phagosome, a sac that encloses the microbe for destruction inside the cell.

Distinction Between Opsonization and Phagocytosis

Opsonization and phagocytosis are related but distinct steps in immune defense. Opsonization tags microbes for easier recognition, while phagocytosis is the physical engulfment and digestion of the microbe by the phagocyte.