Tc cells recognize epitopes only when the latter are held by

• A. MHC proteins.
• B. B cells.
• C. Interleukin-2.
• D. Granzyme.

Answer: (A)

Verified step by step guidance

1. Understand the role of Tc cells, also known as cytotoxic T cells, in the immune system. They are responsible for identifying and destroying infected cells.
2. Learn about epitopes, which are specific parts of an antigen that are recognized by immune cells. Tc cells recognize epitopes presented on the surface of infected cells.
3. Explore the function of Major Histocompatibility Complex (MHC) proteins. These proteins present epitopes on the surface of cells, allowing Tc cells to recognize them.
4. Differentiate between MHC Class I and Class II proteins. Tc cells specifically interact with MHC Class I proteins, which present epitopes from intracellular pathogens.
5. Review the process of antigen presentation. Infected cells display epitopes via MHC Class I proteins, which are then recognized by Tc cells, leading to the destruction of the infected cell.