The largest amount of ATP made by cellular respiration is created by the process of ______________, in the _____________ steps of aerobic cellular respiration.
a) Substrate-level phosphorylation; first.
b) Oxidative phosphorylation; first.
c) Oxidative phosphorylation; final.
d) Substrate-level phosphorylation; final.

• A. Substrate-level phosphorylation; first.
• B. Oxidative phosphorylation; first.
• C. Oxidative phosphorylation; final.
• D. Substrate-level phosphorylation; final.

Answer: (C)

Verified step by step guidance

1. Understand the process of cellular respiration, which consists of glycolysis, the citric acid cycle, and oxidative phosphorylation.
2. Recognize that ATP is produced in different stages of cellular respiration, with the majority being produced during oxidative phosphorylation.
3. Identify that oxidative phosphorylation occurs in the final stage of aerobic cellular respiration, where the electron transport chain and chemiosmosis take place.
4. Differentiate between substrate-level phosphorylation, which occurs in glycolysis and the citric acid cycle, and oxidative phosphorylation, which occurs in the electron transport chain.
5. Conclude that the largest amount of ATP is produced during oxidative phosphorylation in the final steps of aerobic cellular respiration.