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Multiple Choice
An exposure to __________ protects against infection with smallpox.
A
herpes simplex virus
B
influenza virus
C
cowpox virus
D
measles virus
Verified step by step guidance
1
Understand that smallpox is caused by the variola virus, a member of the orthopoxvirus family.
Recall that immunity to smallpox can be achieved through exposure to a related virus that provides cross-protection.
Identify that the cowpox virus, also an orthopoxvirus, shares enough antigenic similarity with the smallpox virus to stimulate an immune response that protects against smallpox.
Recognize that this principle was the basis for Edward Jenner's development of the first vaccine, where exposure to cowpox virus conferred immunity to smallpox.
Conclude that exposure to the cowpox virus protects against infection with smallpox, unlike the other viruses listed which are unrelated.