Purified protein from Bordetella pertussis is used in which type of vaccine?

• A. Live attenuated vaccine
• B. Acellular vaccine
• C. Inactivated whole-cell vaccine
• D. Toxoid vaccine

Answer: (B)

Verified step by step guidance

1. Understand the types of vaccines: Live attenuated vaccines contain weakened live pathogens; inactivated whole-cell vaccines contain killed pathogens; toxoid vaccines contain inactivated toxins; acellular vaccines contain purified components of the pathogen, such as proteins.
2. Identify the nature of the purified protein from Bordetella pertussis: since it is a specific protein component rather than the whole bacterium or its toxin, it fits the description of an acellular vaccine.
3. Recall that acellular vaccines are designed to reduce side effects by including only essential antigens, such as purified proteins, rather than whole cells or toxins.
4. Match the purified protein to the vaccine type: because the vaccine contains purified protein antigens from Bordetella pertussis, it is classified as an acellular vaccine.
5. Conclude that the purified protein from Bordetella pertussis is used in acellular vaccines, which are distinct from live attenuated, inactivated whole-cell, or toxoid vaccines.