GOB Chemistry

Learn the toughest concepts covered in your GOB - General, Organic, and Biological Chemistry class with step-by-step video tutorials and practice problems.

Acids and Bases

Henderson-Hasselbalch Equation

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Henderson-Hasselbalch Equation Concept 1

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Henderson-Hasselbalch Equation Example 1

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Problem

Calculate the pH of a solution formed by mixing 200 mL of a 0.400 M C2H5NH2 solution with 350 mL of a 0.450 M C2H5NH3solution. (Kb of C2H5NHis 5.6 x 10 -4).

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Henderson-Hasselbalch Equation Example 2

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Henderson-Hasselbalch Equation Example 3

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Problem

Determine how many grams of sodium acetate, NaCH3CO2 (MW:82.05 g/mol), you would mix into enough 0.065 M acetic acid CH3CO2H (MW:60.05 g/mol) to prepare 3.2 L of a buffer with a pH of 4.58. The Ka is 1.8 x 10-5.

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Henderson-Hasselbalch Equation Example 4

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Problem

A buffer solution is made by combining a weak acid with its conjugate salt. What will happen to the pH if the solution is diluted to one-fourth of its original concentration?