Which of the following statements is true regarding the catabolism of ${\mathrm{glucose}}_1$ during glycolysis?

• A. Glycolysis produces ${\mathrm{CO}}_2$ as a byproduct.
• B. Glycolysis occurs in the mitochondria of eukaryotic cells.
• C. Glycolysis results in the net production of $2$ $\mathrm{ATP}$ molecules per $\mathrm{glucose}$ molecule.
• D. Glycolysis requires oxygen to proceed.

Answer: (C)

Verified step by step guidance

1. Begin by understanding the process of glycolysis, which is the metabolic pathway that converts glucose into pyruvate, releasing energy in the form of ATP.
2. Recognize that glycolysis occurs in the cytoplasm of cells, not in the mitochondria. This is a key distinction from other metabolic processes like the Krebs cycle.
3. Identify that glycolysis is an anaerobic process, meaning it does not require oxygen to proceed. This is important for understanding how cells generate energy in low-oxygen conditions.
4. Understand that glycolysis does not produce carbon dioxide as a byproduct. Carbon dioxide is produced in later stages of cellular respiration, such as the Krebs cycle and oxidative phosphorylation.
5. Note that glycolysis results in a net production of 2 ATP molecules per glucose molecule. This is because 4 ATP molecules are produced, but 2 are consumed during the process, leading to a net gain of 2 ATP.