Organic Chemistry

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7. Substitution Reactions

Substitution Comparison

How can we tell which mechanism to use? This question will get more complicated unfortunately, but for now we can use the following factors to answer this question.

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concept

How do we predict if the mechanism is SN1 or SN2?

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When given a substitution reaction, use the following two factors to determine the mechanism:

Nucleophile Strength:              SN1 =   WEAK               SN2 = STRONG

Leaving Group Substitution:    SN1  = 3° > 2°                 SN2 = 0° > 1° > 2°

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Predict the product of the reaction

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Predict the product of the reaction