Develop syntheses for the following compounds.
As starting mater...

Question

Develop syntheses for the following compounds. As starting materials, you may use cyclopentanol, alcohols containing no more than four carbon atoms, and any common reagents and solvents. (c)

Accepted Answer

Hey everyone and welcome back in today's video, we are going to learn how to solve the following problem which asks us to devise an approach for the synthesis of the following molecule. You can start with psycho hexen on any region that contains four carbon atoms or less in any required regent or solvent. Okay, so essentially what we're going to do here, we're going to think about psycho Heche salon and we're going to draw it because this is a good hint for us for the starting material cycle. Hex alone is a key tone which contains a six member ring and this starting material looks similar to the final box side that we want to form. So what is the way to get at ip oxide? We call that the general reaction that we know for the formation of ip oxides is the oxidation of al kins. Now, how does that look? We're taking our elkin right. And we are essentially treating it with meta chloral peroxide, benzoyl Cassidy. And that is how we get our ip oxide. So this would be our last step, right. We just understand that we somehow want to get an al keen out of psycho hexen on. And why don't we just form an alcohol then essentially eliminate performing elimination. Form an ALc in and then oxidize it. So that's our general logic, number one. Get an alcohol out of our carbon compound number to eliminate And then number three use em CPB A. So okay, so let's get our alcohol. This is a key tone. If you want to get an alcohol, we want to reduce that compound. Right, So our first reaction is the reduction reaction which we may use any of the two reducing agents that were familiar with sodium borough hydrate or lithium aluminum hydride. But lithium aluminum hydrate is a strong reducing agent. It's just sufficient to use a mild one. So if we use the mild reducing agent, we get our alcohol in this case as well. If we draw our results in alcohol which is psycho hexagonal, this is the structure we get Now our next step is to eliminate performing elimination reaction on that alcohol so we can get that L keen that we can later on oxidized. And to do that, we are just going to use and acid catalyzed dehydration. In other words, everything that we need to use here is sulfuric acid or we can just say addition of strongly acidic medium because there are beta hydrants here in particular. You may think about it as the mechanism suggests, right, We are essentially protein ating a wage. First it except the proton, we have a good leaving group. Then we're forming a carbo Karen and in an E one mechanism, Right? This is an E one mechanism the water molecule and attacks were forming our double bond here followed by the loss of water. That's how we are forming our Elkin and that's amazing. Right? We got our Elkin. We already see oxidize that we know that Elkins when treated with methyl chloride peroxide. Benzoyl casa, produced the box sides. So that would be our last step. We can just say that the last step is addition of meta chloral proxy benzoate acid, which produces the required ip oxide. We're using that double bond and into the formation of an Ipaq side and we got it. That's our final structure. So the reaction pathway is as follows, we start with psycho hex known just to suggest that reduce it into an alcohol performing elimination reaction and an acid catalyzed dehydration mechanism form an AL king. And when we get our alkaline, we oxidize that using EM CPB A to get our ip oxide. Now the correct answer to the small punctures question is C However, if you have any questions, don't have states, leave your comment down below in the comment section and thank you for watching

Develop syntheses for the following compounds. As starting materials, you may use cyclopentanol, alcohols containing no more than four carbon atoms, and any common reagents and solvents. (c)

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