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Multiple Choice
Which of the following is the correct Fischer projection for ?
A
A vertical backbone with, from top to bottom, , left: , right: ; left: , right: ; left: , right: ; left: , right: ; and at the bottom
B
A vertical backbone with, from top to bottom, , left: , right: ; left: , right: ; left: , right: ; left: , right: ; and at the bottom
C
A vertical backbone with, from top to bottom, , left: , right: ; left: , right: ; left: , right: ; left: , right: ; and at the bottom
D
A vertical backbone with, from top to bottom, , left: , right: ; left: , right: ; left: , right: ; left: , right: ; and at the bottom
Verified step by step guidance
1
Recall that D-glucose is an aldohexose with the aldehyde group (CHO) at the top of the Fischer projection and the primary alcohol group (CH\_2OH) at the bottom.
Identify the stereocenters in D-glucose: carbons 2, 3, 4, and 5 are chiral centers, each with an OH and an H attached.
Remember the configuration of D-glucose at each chiral center from top to bottom: at C2, the OH is on the right; at C3, the OH is on the left; at C4, the OH is on the right; and at C5, the OH is on the right.
Translate this into the Fischer projection: the vertical backbone is the carbon chain with CHO at the top and CH\_2OH at the bottom; horizontal lines represent bonds coming out of the plane (towards the viewer), so OH groups on the right are drawn on the right side, and those on the left are drawn on the left side.
Compare the given options with this pattern to select the correct Fischer projection that matches the OH and H positions for D-glucose.