The most stable form of the common sugar glucose contains a six-membered ring in the chair conformation with all the substituents equatorial. Draw this most stable conformation of glucose.

Verified step by step guidance

1. Identify the structure of glucose: Glucose is a six-carbon sugar with the molecular formula C6H12O6. In its most stable form, it adopts a six-membered ring structure known as a pyranose form.
2. Understand the chair conformation: The chair conformation is a three-dimensional shape that cyclohexane rings can adopt to minimize steric strain. In this conformation, substituents can be in axial (up or down) or equatorial (around the equator of the ring) positions.
3. Determine the orientation of substituents: For glucose, the most stable conformation is when all the hydroxyl (OH) groups and the CH2OH group are in equatorial positions to minimize steric hindrance and maximize stability.
4. Draw the chair conformation: Start by sketching a cyclohexane chair structure. Place the oxygen atom in the ring and arrange the carbon atoms around it. Ensure that all substituents (OH groups and CH2OH) are positioned equatorially.
5. Verify the structure: Double-check that all substituents are in the equatorial position and that the overall structure represents the most stable form of glucose. This ensures that the drawing accurately reflects the most stable conformation.

Key Concepts

Chair Conformation

The chair conformation is a three-dimensional shape that cyclohexane rings adopt to minimize steric strain and torsional strain. In this conformation, the carbon atoms are arranged in a staggered manner, resembling a chair, which allows for the most stable arrangement of atoms and substituents. This conformation is crucial for understanding the stability of glucose in its most stable form.

Equatorial Position

In cyclohexane rings, substituents can occupy either axial or equatorial positions. Equatorial positions are located around the equator of the ring and are generally more stable due to reduced steric hindrance compared to axial positions. For glucose, having all substituents in equatorial positions minimizes steric clashes, contributing to its stability.

Glucose Structure

Glucose is a six-carbon sugar with an aldehyde group and five hydroxyl groups. In its most stable form, glucose adopts a pyranose ring structure, resembling a cyclohexane ring in the chair conformation. Understanding the arrangement of hydroxyl groups and the ring structure is essential for drawing and recognizing the most stable conformation of glucose.